Selected Publications

(for more publications, please refer to PubMed)

C. Huang, C. Lewis, N.A. Borg, M. Canals, H. Diep, G. Drummond, R.J. Goode, R.B. Schittenhelm, A. Vinh, M. Zhu, B. Kemp-Harper*, O. Kleifeld*, M.J. Stone*, Proteomic Identification of Interferon-induced Proteins with Tetratricopeptide Repeats (IFITs) as Markers of M1 Macrophage Polarization, J. Proteome Res. (2018) acs.jproteome.7b00828. doi:10.1021/acs.jproteome.7b00828.

R. Meledin, S. Mali, O. Kleifeld*, A. Brik* Activity-Based Probes Developed by Applying Sequential Dehydroalanine Strategy on Expressed Proteins Reveal a Potential α-globin Modulating Deubiquitinase, Angew. Chemie Int. Ed. (2018). doi:10.1002/anie.201800032.

A.L. Samson, B. Ho, A.E. Au, S.M. Schoenwaelder, M.J. Smyth, S.P. Bottomley, O. Kleifeld*, R.L. Medcalf*, Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells, Open Biol. 6 (2016) 160098. doi:10.1098/rsob.160098.

S.K. Singh, I. Sahu, S.M. Mali, H.P. Hemantha, O. Kleifeld, M.H. Glickman, A. Brik, Synthetic Uncleavable Ubiquitinated Proteins Dissect Proteasome Deubiquitination and Degradation, and Highlight Distinctive Fate of Tetraubiquitin, J. Am. Chem. Soc. 138 (2016) 16004–16015. doi:10.1021/jacs.6b09611.

M.A. Rees, O. Kleifeld, P.K. Crellin, B. Ho, T.P. Stinear, A.I. Smith, R.L. Coppel, Proteomic Characterization of a Natural Host–Pathogen Interaction: Repertoire of in Vivo Expressed Bacterial and Host Surface-Associated Proteins, J. Proteome Res. 14 (2015) 120–132. doi:10.1021/pr5010086.

M.A. Rees, T.P. Stinear, R.J.A. Goode, R.L. Coppel, A.I. Smith, O. Kleifeld, Changes in protein abundance are observed in bacterial isolates from a natural host, Front. Cell. Infect. Microbiol. 5 (2015) 71. doi:10.3389/fcimb.2015.00071.

I. Ziv, Y. Matiuhin, D.S. Kirkpatrick, Z. Erpapazoglou, S. Leon, M. Pantazopoulou, W. Kim, S.P. Gygi, R. Haguenauer-Tsapis, N. Reis, M.H. Glickman*, O. Kleifeld*, A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis., Mol. Cell. Proteomics. 10 (2011) M111.009753.

O. Kleifeld, A. Doucet, A. Prudova, U. auf dem Keller, M. Gioia, J.N. Kizhakkedathu, C.M. Overall, Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates., Nat. Protoc. 6 (2011) 1578–611. .

O. Kleifeld, A. Doucet, U. auf dem Keller, A. Prudova, O. Schilling, R.K. Kainthan, A.E. Starr, L.J. Foster, J.N. Kizhakkedathu, C.M. Overall, Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products., Nat. Biotechnol. 28 (2010) 281–8.

  • Equal contribution by last and corresponding authors